MTR ELISA kits are immunoassay tools for the measurement of the protein 5-methyltetrahydrofolate-homocysteine methyltransferase, which is encoded by the MTR gene in humans. Functionally, this protein is known to catalyze the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. The canonical protein structure is reported to have an amino acid length of 1265 residues, a mass of 140.5 kDa, and is a member of the Vitamin-B12 dependent methionine synthase protein family. It is known to be localized in the cytoplasm and is widely expressed across many tissue types. As many as 2 protein isoforms have been reported. The MTR gene has been associated with the disease, Homocystinuria-megaloblastic anemia. Other alias names for this target include MS, cblG, methionine synthase, 5-methyltetrahydrofolate-homocysteine methyltransferase 1, cobalamin-dependent methionine synthase, and HMAG.
Some MTR ELISA kits can detect targets at levels as low as 0.05 ng/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.