The following insulin induced gene 1 ELISA kits are useful research tools for the measurement of insulin induced gene 1 in biological samples. In humans this protein is encoded by the INSIG1 gene. This protein is reported to be an oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR. The canonical protein structure is reported to have an amino acid length of 277 residues, a mass of 30 kDa, and is a member of the INSIG protein family. Its subcellular location is known to be in the ER. In addition, it is reported to be expressed in all tissues tested with highest expression in the liver. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. This protein may also be known as insulin-induced gene 1 protein, INSIG-1 membrane protein, and CL6.
Some insulin induced gene 1 ELISA kits can detect targets at levels as low as 0.313 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.