DTX1 ELISA kits are immunoassay tools for the measurement of the protein deltex E3 ubiquitin ligase 1, which is encoded by the DTX1 gene in humans. Functionally, this protein is known to function as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). The canonical protein structure is reported to have an amino acid length of 620 residues, a mass of 67.4 kDa, and is a member of the Deltex protein family. It is known to be localized in the nucleus and cytoplasm and is widely expressed across many tissue types. The protein has been noted to be post-translationally ubiquitinated. Other alias names for this target include hDx-1, E3 ubiquitin-protein ligase DTX1, RING-type E3 ubiquitin transferase DTX1, deltex 1, E3 ubiquitin ligase, deltex homolog 1, and RNF140.
The detection range for different DTX1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.