The following AP2 associated kinase 1 ELISA kits are useful research tools for the measurement of AP2 associated kinase 1 in biological samples. In humans this protein is encoded by the AAK1 gene. This protein is reported to regulate clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. The canonical protein structure is reported to have an amino acid length of 961 residues, a mass of 103.9 kDa, and is a member of the Ser/Thr protein kinase protein family. Its subcellular location is known to be in the cell membrane. In addition, it is notably expressed in the brain, heart and liver. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. This protein may also be known as AP2-associated protein kinase 1 and adaptor-associated kinase 1.
The detection range for different AP2 associated kinase 1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.