TCF7L2 ELISA kits are immunoassay tools for the measurement of the protein transcription factor 7 like 2, which is encoded by the TCF7L2 gene in humans. Functionally, this protein is known to participate in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. The canonical protein structure is reported to have an amino acid length of 619 residues, a mass of 67.9 kDa, and is a member of the TCF/LEF protein family. It is known to be localized in the nucleus and is notably expressed in epithelium from small intestine, with the highest expression at the top of the crypts and a gradient of expression from crypt to villus. As many as 17 protein isoforms have been reported. The protein has been noted to be post-translationally sumoylated and phosphorylated. The TCF7L2 gene has been associated with the disease, Type 2 diabetes mellitus. Other alias names for this target include TCF4, HMG box transcription factor 4, T-cell factor 4, T-cell-specific transcription factor 4, hTCF-4, and TCF-4.
There are TCF7L2 ELISA kits that can detect a target at concentrations as low as 62.5 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.