NOTCH3 ELISA kits are immunoassay tools for the measurement of the protein notch receptor 3, which is encoded by the NOTCH3 gene in humans. Functionally, this protein is known to function as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. The canonical protein structure is reported to have an amino acid length of 2321 residues, a mass of 243.6 kDa, and is a member of the NOTCH protein family. It is known to be localized in the nucleus and cell membrane and is widely expressed across many tissue types. The protein has been noted to be post-translationally glycosylated, cleaved and phosphorylated. The NOTCH3 gene has been associated with the disease, Cerebral arteriopathy. Other alias names for this target include CADASIL1, CASIL, IMF2, LMNS, neurogenic locus notch homolog protein 3, Notch homolog 3, and CADASIL.
There are NOTCH3 ELISA kits that can detect a target at concentrations as low as 46.875 pg/mL and as high as 25 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.