MAP3K7 ELISA kits are immunoassay tools for the measurement of the protein mitogen-activated protein kinase kinase kinase 7, which is encoded by the MAP3K7 gene in humans. Functionally, this protein is known to be a serine/threonine kinase that acts as an essential component of the MAP kinase signal transduction pathway. The canonical protein structure is reported to have an amino acid length of 606 residues, a mass of 67.2 kDa, and is a member of the STE Ser/Thr protein kinase protein family. It is known to be localized in the cell membrane and cytoplasm. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated, acetylated and phosphorylated. The MAP3K7 gene has been associated with the disease, Frontometaphyseal dysplasia. Other alias names for this target include FMD2, MEKK7, TAK1, TGF1a, TGF-beta activated kinase 1, transforming growth factor-beta-activated kinase 1, and CSCF.
The detection range for different MAP3K7 ELISA kits can vary, with some assays measuring target concentrations as low as 25 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.