CFTR ELISA kits are immunoassay tools for the measurement of the protein CF transmembrane conductance regulator, which is encoded by the CFTR gene in humans. Functionally, this protein is known to be involved in cholesterol metabolism and homeostasis and cellular localization. The canonical protein structure is reported to have an amino acid length of 1480 residues, a mass of 168.1 kDa, and is a member of the ABCC protein family. It is known to be localized in the nucleus, ER, and cell membrane and is reported to be expressed in the respiratory airway, including bronchial epithelium, and in the female reproductive tract, including oviduct. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The CFTR gene has been associated with the disease, Cystic fibrosis. Other alias names for this target include ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1, cystic fibrosis transmembrane conductance regulator, and ABC35.
The detection range for different CFTR ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.