HDAC6 ELISA kits are immunoassay tools for the measurement of the protein histone deacetylase 6, which is encoded by the HDAC6 gene in humans. Functionally, this protein is known to be important for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). The canonical protein structure is reported to have an amino acid length of 1215 residues, a mass of 131.4 kDa, and is a member of the Histone deacetylase protein family. It is known to be localized in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated, sumoylated, acetylated and phosphorylated. The HDAC6 gene has been associated with the disease, Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Other alias names for this target include HD6, JM21, PPP1R90, protein phosphatase 1, regulatory subunit 90, tubulin-lysine deacetylase HDAC6, and CPBHM.
The detection range for different HDAC6 ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.