MMP2 ELISA kits are immunoassay tools for the measurement of the protein matrix metallopeptidase 2, which is encoded by the MMP2 gene in humans. Functionally, this protein is reported to be a ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. The canonical protein structure is reported to have an amino acid length of 660 residues, a mass of 73.9 kDa, and is a member of the Peptidase M10A protein family. It is known to be localized in the nucleus and extracellular matrix. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated, cleaved and phosphorylated. The MMP2 gene has been associated with the disease, Multicentric osteolysis, nodulosis, and arthropathy. Other alias names for this target include CLG4A, MMP-II, MONA, TBE-1, 72 kDa type IV collagenase, and CLG4.
The detection range for different MMP2 ELISA kits can vary, with some assays measuring target concentrations as low as 3.12 pg/mL and as high as 3000 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.