PURA ELISA kits are immunoassay tools for the measurement of the protein purine rich element binding protein A, which is encoded by the PURA gene in humans. Functionally, this protein is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. The canonical protein structure is reported to have an amino acid length of 322 residues, a mass of 34.9 kDa, and is a member of the PUR DNA-binding protein family. It is known to be localized in the nucleus. The PURA gene has been associated with the disease, Neurodevelopmental disorder with neonatal respiratory insufficiency, hypotonia, and feeding difficulties. Other alias names for this target include NEDRIHF, PUR-ALPHA, PUR1, PURALPHA, transcriptional activator protein Pur-alpha, and MRD31.
The detection range for different PURA ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.