JAK2 ELISA kits are immunoassay tools for the measurement of the protein Janus kinase 2, which is encoded by the JAK2 gene in humans. Functionally, this protein is a type of non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. The canonical protein structure is reported to have an amino acid length of 1132 residues, a mass of 130.7 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the membrane, nucleus, and cytoplasm. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The JAK2 gene has been associated with the disease, Budd-Chiari syndrome. Other alias names for this target include tyrosine-protein kinase JAK2, Janus kinase 2 (a protein tyrosine kinase), and JTK10.
The detection range for different JAK2 ELISA kits can vary, with some assays measuring target concentrations as low as 78.1 pg/mL and as high as 60 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.