The HER-2/neu ELISA kits listed below utilize specific antibodies for the plate-based assay of HER-2/neu in various samples. HER-2/neu is another term for the ERBB2 gene, which encodes the protein, erb-b2 receptor tyrosine kinase 2 in humans. It has been reported that HER-2/neu plays a role in receptor-mediated signaling pathways and cardiac tissue development, among other functions. Structurally, the ERBB2 protein is described to be 1255 amino acid residues in length and 137.9 kilodaltons in mass. It is localized to the cell membrane of the cell. In terms of tissue specificity, it is reported to be expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth. This protein is known to be phosphorylated and glycosylated. Other names for this target antigen include CD340, HER-2, and HER-2/neu. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.