ADSL ELISA kits are immunoassay tools for the measurement of the protein adenylosuccinate lyase, which is encoded by the ADSL gene in humans. Functionally, this protein is known to catalyze two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. The canonical protein structure is reported to have an amino acid length of 484 residues, a mass of 54.9 kDa, and is a member of the Lyase 1 protein family. It is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The ADSL gene has been associated with the disease, Adenylosuccinase deficiency. Other alias names for this target include ASASE, ASL, adenylosuccinase, and AMPS.
There are ADSL ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.