SEMA7A ELISA kits are immunoassay tools for the measurement of the protein semaphorin 7A (John Milton Hagen blood group), which is encoded by the SEMA7A gene in humans. Functionally, this protein is known to play an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. The canonical protein structure is reported to have an amino acid length of 666 residues, a mass of 74.8 kDa, and is a member of the Semaphorin protein family. It is known to be localized in the cell membrane and is notably expressed in skin keratinocytes and on endothelial cells from skin blood vessels. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The SEMA7A gene has been associated with the disease, Cholestasis. Other alias names for this target include CDw108, H-SEMA-K1, H-Sema-L, JMH, PFIC11, SEMAK1, SEMAL, and CD108.
There are SEMA7A ELISA kits that can detect a target at concentrations as low as 31.25 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.