PMS2 ELISA kits are immunoassay tools for the measurement of the protein PMS1 homolog 2, mismatch repair system component, which is encoded by the PMS2 gene in humans. Functionally, this protein is a known component of the post-replicative DNA mismatch repair system (MMR). The canonical protein structure is reported to have an amino acid length of 862 residues, a mass of 95.8 kDa, and is a member of the DNA mismatch repair MutL/HexB protein family. It is known to be localized in the nucleus. As many as 4 protein isoforms have been reported. The PMS2 gene has been associated with the disease, Lynch syndrome. Other alias names for this target include LYNCH4, MLH4, MMRCS4, PMS2CL, PMSL2, mismatch repair endonuclease PMS2, DNA mismatch repair protein PMS2, and HNPCC4.
The detection range for different Pms2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.