PDGFRB ELISA kits are immunoassay tools for the measurement of the protein platelet derived growth factor receptor beta, which is encoded by the PDGFRB gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. The canonical protein structure is reported to have an amino acid length of 1106 residues, a mass of 124 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the cytoplasmic vesicles, lysosomes, and cell membrane. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The PDGFRB gene has been associated with the disease, Myeloproliferative disorder chronic with eosinophilia. Other alias names for this target include IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, and CD140B.
Some PDGFRB ELISA kits can detect targets at levels as low as 15 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.