NBN ELISA kits are immunoassay tools for the measurement of the protein nibrin, which is encoded by the NBN gene in humans. Functionally, this protein is a known component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The canonical protein structure is reported to have an amino acid sequence of 754 residues and a mass of 85 kDa. It is known to be localized in the nucleus and is ubiquitously expressed across many tissue types. The protein has been noted to be post-translationally phosphorylated. The NBN gene has been associated with the disease, Nijmegen breakage syndrome. Other alias names for this target include AT-V2, ATV, NBS, NBS1, P95, Nijmegen breakage syndrome 1 (nibrin), cell cycle regulatory protein p95, and AT-V1.
Some NBN ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 5000 pg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.