GRIN2B ELISA kits are immunoassay tools for the measurement of the protein glutamate ionotropic receptor NMDA type subunit 2B, which is encoded by the GRIN2B gene in humans. Functionally, this protein is known to be a component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. The canonical protein structure is reported to have an amino acid length of 1484 residues, a mass of 166.4 kDa, and is a member of the Glutamate-gated ion channel (TC 1.A.10.1) protein family. It is known to be localized in the cell membrane, lysosomes and cytoplasm. The protein has been noted to be post-translationally phosphorylated and glycosylated. The GRIN2B gene has been associated with the disease, Intellectual developmental disorder. Other alias names for this target include EIEE27, GluN2B, MRD6, NMDAR2B, NR2B, NR3, hNR3, and DEE27.
Some GRIN2B ELISA kits can detect targets at levels as low as 20 ng/L and as high as 30 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.