CXCR4 ELISA kits are immunoassay tools for the measurement of the protein C-X-C motif chemokine receptor 4, which is encoded by the CXCR4 gene in humans. Functionally, this protein is a known receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. The canonical protein structure is reported to have an amino acid length of 352 residues, a mass of 39.7 kDa, and is a member of the G-protein coupled receptor 1 protein family. It is known to be localized in the lysosomes and cell membrane. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally O-glycosylated, N-glycosylated, ubiquitinated, sulfated and phosphorylated. The CXCR4 gene has been associated with the disease, WHIM syndrome. Other alias names for this target include D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, and CD184.
There are CXCR4 ELISA kits that can detect a target at concentrations as low as 15.6 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.