CCR5 ELISA kits are immunoassay tools for the measurement of the protein C-C motif chemokine receptor 5, which is encoded by the CCR5 gene in humans. Functionally, this protein is a known receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. The canonical protein structure is reported to have an amino acid length of 352 residues, a mass of 40.5 kDa, and is a member of the G-protein coupled receptor 1 protein family. It is known to be localized in the cell membrane and is reported to be highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. The protein has been noted to be post-translationally O-glycosylated, N-glycosylated, palmitoylated, sulfated and phosphorylated. The CCR5 gene has been associated with the disease, Type 1 diabetes mellitus. Other alias names for this target include CCCKR5, CD195, CKR-5, CKR5, CMKBR5, IDDM22, C-C chemokine receptor type 5, and CC-CKR-5.
There are CCR5 ELISA kits that can detect a target at concentrations as low as 5 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.