CASP7 ELISA kits are immunoassay tools for the measurement of the protein caspase 7, which is encoded by the CASP7 gene in humans. Functionally, this protein is known to be a thiol protease involved in different programmed cell death processes, such as apoptosis, pyroptosis or granzyme-mediated programmed cell death, by proteolytically cleaving target proteins. The canonical protein structure is reported to have an amino acid length of 303 residues, a mass of 34.3 kDa, and is a member of the Peptidase C14A protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be highly expressed in the lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and phosphorylated. Other alias names for this target include ICE-LAP3, LICE2, MCH3, ICE-like apoptotic protease 3, apoptotic protease MCH-3, and CMH-1.
Some CASP7 ELISA kits can detect targets at levels as low as 20 ng/L and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.