BLNK ELISA kits are immunoassay tools for the measurement of the protein B cell linker, which is encoded by the BLNK gene in humans. Functionally, this protein is known to function as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. The canonical protein structure is reported to have an amino acid sequence of 456 residues and a mass of 50.5 kDa. It is known to be localized in the cell membrane and cytoplasm and is reported to be expressed in B-cell lineage and fibroblast cell lines. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The BLNK gene has been associated with the disease, Agammaglobulinemia. Other alias names for this target include BASH, BLNK-S, LY57, SLP-65, SLP65, bca, B-cell linker protein, and AGM4.
Some BLNK ELISA kits can detect targets at levels as low as 62.5 pg/mL and as high as 60 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.