The following transmembrane immune signaling adaptor TYROBP ELISA kits are useful research tools for the measurement of transmembrane immune signaling adaptor TYROBP in biological samples. In humans this protein is encoded by the TYROBP gene. This protein is reported to be an adapter protein, which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors. The canonical protein structure is reported to have an amino acid length of 113 residues, a mass of 12.2 kDa, and is a member of the TYROBP protein family. Its subcellular location is known to be in the cell membrane. In addition, it is reported to be expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy. This protein may also be known as KARAP, PLOSL, PLOSL1, TYRO protein tyrosine kinase-binding protein, DNAX adaptor protein 12, and DAP12.
There are transmembrane immune signaling adaptor TYROBP ELISA kits that can detect a target at concentrations as low as 0.15 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.