The following rubicon autophagy regulator ELISA kits are useful research tools for the measurement of rubicon autophagy regulator in biological samples. In humans this protein is encoded by the RUBCN gene. This protein is reported to inhibit PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. The canonical protein structure is reported to have an amino acid sequence of 972 residues and a mass of 108.6 kDa. Its subcellular location is known to be in the lysosomes. As many as 3 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Spinocerebellar ataxia. This protein may also be known as RUBICON, SCAR15, run domain Beclin-1-interacting and cysteine-rich domain-containing protein, RUN and cysteine rich domain containing beclin 1 interacting protein, and KIAA0226.
The detection range for different rubicon autophagy regulator ELISA kits can vary, with some assays measuring target concentrations as low as 0.31 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.