The following neurofilament light chain ELISA kits are useful research tools for the measurement of neurofilament light chain in biological samples. In humans this protein is encoded by the NEFL gene. This protein has been described to function in neuronal development. The canonical protein structure is reported to have an amino acid length of 543 residues, a mass of 61.5 kDa, and is a member of the Intermediate filament protein family. Its subcellular location is known to be in the cell projections and cytoplasm. In certain instances, it is also post-translationally O-glycosylated, ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Charcot-Marie-Tooth disease. This protein may also be known as CMT2E, CMTDIG, NF-L, NF68, NFL, PPP1R110, neurofilament light polypeptide, and CMT1F.
There are neurofilament light chain ELISA kits that can detect a target at concentrations as low as 1 ng/L and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.