The following shugoshin 1 ELISA kits are useful research tools for the measurement of shugoshin 1 in biological samples. In humans this protein is encoded by the SGO1 gene. This protein is known to play an important role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. The canonical protein structure is reported to have an amino acid length of 561 residues, a mass of 64.2 kDa, and is a member of the Shugoshin protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is widely expressed across many tissue types. As many as 7 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Chronic atrial and intestinal dysrhythmia. This protein may also be known as shugoshin 1AB protein, shugoshin 1CD protein, shugoshin 1EF protein, shugoshin 1GH protein, shugoshin 1KL protein, and serologically defined breast cancer antigen NY-BR-85.
The detection range for different shugoshin 1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.