The following MDM2 proto-oncogene ELISA kits are useful research tools for the measurement of MDM2 proto-oncogene in biological samples. In humans this protein is encoded by the MDM2 gene. This protein has been described to function in the apoptotic pathway and blood vessel development. The canonical protein structure is reported to have an amino acid length of 491 residues, a mass of 55.2 kDa, and is a member of the MDM2/MDM4 protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is ubiquitously expressed across many tissue types. As many as 11 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Lessel-Kubisch syndrome. This protein may also be known as HDMX, LSKB, hdm2, E3 ubiquitin-protein ligase Mdm2, MDM2 oncogene, E3 ubiquitin protein ligase, and ACTFS.
The detection range for different MDM2 proto-oncogene ELISA kits can vary, with some assays measuring target concentrations as low as 20 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.