KMT5B ELISA kits are immunoassay tools for the measurement of the protein lysine methyltransferase 5B, which is encoded by the KMT5B gene in humans. Functionally, this protein is a known histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity. The canonical protein structure is reported to have an amino acid length of 885 residues, a mass of 99.2 kDa, and is a member of the Histone-lysine methyltransferase protein family. It is known to be localized in the nucleus and chromosomes. As many as 3 protein isoforms have been reported. The KMT5B gene has been associated with the disease, Intellectual developmental disorder. Other alias names for this target include CGI85, MRD51, SUV420H1, histone-lysine N-methyltransferase KMT5B, and CGI-85.
Some KMT5B ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.