HNF4A ELISA kits are immunoassay tools for the measurement of the protein hepatocyte nuclear factor 4 alpha, which is encoded by the HNF4A gene in humans. Functionally, this protein is a reported transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. The canonical protein structure is reported to have an amino acid length of 474 residues, a mass of 52.8 kDa, and is a member of the Nuclear hormone receptor protein family. It is known to be localized in the nucleus. As many as 7 protein isoforms have been reported. The protein has been noted to be post-translationally acetylated and phosphorylated. The HNF4A gene has been associated with the disease, Maturity-onset diabetes of the young. Other alias names for this target include HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, and FRTS4.
Some HNF4A ELISA kits can detect targets at levels as low as 15.625 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.