DTNBP1 ELISA kits are immunoassay tools for the measurement of the protein dystrobrevin binding protein 1, which is encoded by the DTNBP1 gene in humans. Functionally, this protein is a known component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. The canonical protein structure is reported to have an amino acid length of 351 residues, a mass of 39.5 kDa, and is a member of the Dysbindin protein family. It is known to be localized in the cell membrane, nucleus, cytoplasmic vesicles, ER, and cytoplasm and is notably expressed in the brain, in neurons and in neuropil. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The DTNBP1 gene has been associated with the disease, Hermansky-Pudlak syndrome. Other alias names for this target include BLOC-1 subunit 8, Hermansky-Pudlak syndrome 7 protein, biogenesis of lysosomal organelles complex-1, subunit 8, biogenesis of lysosome-related organelles complex 1 subunit 8, dysbindin-1, and dysbindin.
There are DTNBP1 ELISA kits that can detect a target at concentrations as low as 15.6 pg/mL and as high as 5000 pg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.