CMTM6 ELISA kits are immunoassay tools for the measurement of the protein CKLF like MARVEL transmembrane domain containing 6, which is encoded by the CMTM6 gene in humans. Functionally, this protein is a reported master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. The canonical protein structure is reported to have an amino acid length of 183 residues, a mass of 20.4 kDa, and is a member of the Chemokine-like factor protein family. It is known to be localized in the cell membrane and is reported to be expressed in the leukocytes, placenta and testis. Other alias names for this target include PRO2219, CKLF-like MARVEL transmembrane domain-containing protein 6, chemokine-like factor super family 6, chemokine-like factor superfamily 6, chemokine-like factor superfamily member 6, and CKLFSF6.
The detection range for different CMTM6 ELISA kits can vary, with some assays measuring target concentrations as low as 6.9 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.