The THP ELISA kits listed below utilize specific antibodies for the plate-based assay of THP in various samples. THP is another term for the UMOD gene, which encodes the protein, uromodulin in humans. It has been reported that THP plays a role in the apoptotic pathway and autophagy pathways, among other functions. Structurally, the UMOD protein is 640 amino acid residues in length and 69.8 kilodaltons in mass. However, as many as 5 protein isoforms have been identified. It is localized to the cell membrane of the cell. In terms of tissue specificity, it is reported to be expressed in the tubular cells of the kidney. This protein is known to be N-glycosylated and cleaved. Other names for this target antigen include ADMCKD2, ADTKD1, and FJHN.
There are THP ELISA kits that can detect a target at concentrations as low as 78.125 pg/mL and as high as 200 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.