IREB2 ELISA kits are immunoassay tools for the measurement of the protein iron responsive element binding protein 2, which is encoded by the IREB2 gene in humans. Functionally, this protein is reported to be a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. The canonical protein structure is reported to have an amino acid length of 963 residues, a mass of 105.1 kDa, and is a member of the Aconitase/IPM isomerase protein family. It is known to be localized in the cytoplasm. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated. The IREB2 gene has been associated with the disease, Neurodegeneration. Other alias names for this target include IRE-BP 2, IRE-BP2, IRP2, IRP2AD, NDCAMA, iron regulatory protein 2, and ACO3.
There are IREB2 ELISA kits that can detect a target at concentrations as low as 15.625 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.