The following Peroxidasin ELISA kits are useful research tools for the measurement of peroxidasin in biological samples. In humans this protein is encoded by the PXDN gene. This protein is known to catalyze the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV/COL4A1 NC1 hexamer. The canonical protein structure is reported to have an amino acid length of 1479 residues, a mass of 165.3 kDa, and is a member of the Peroxidase protein family. Its subcellular location is known to be in the ER, extracellular matrix, and is secreted. In addition, it is noted to be expressed at higher levels in heart, lung, ovary, spleen, intestine and placenta, and at lower levels in liver, colon, pancreas, kidney, thymus, skeletal muscle and prostate. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally N-glycosylated and cleaved. The gene encoding this protein has been associated with the disease, Anterior segment dysgenesis. This protein may also be known as COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO, and ASGD7.
The detection range for different Peroxidasin ELISA kits can vary, with some assays measuring target concentrations as low as 50 ng/L and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.