ACE2 ELISA kits are immunoassay tools for the measurement of the protein angiotensin converting enzyme 2, which is encoded by the ACE2 gene in humans. Functionally, this protein is known to be an important counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. The canonical protein structure is reported to have an amino acid length of 805 residues, a mass of 92.5 kDa, and is a member of the Peptidase M2 protein family. It is known to be localized in the cell membrane, cytoplasm, and is secreted and is reported to be expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, cleaved and phosphorylated. Other alias names for this target include angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin I converting enzyme 2, angiotensin-converting enzyme homolog, and ACE-related carboxypeptidase.
Some ACE2 ELISA kits can detect targets at levels as low as 2 ng/L and as high as 255 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.