GDNF ELISA kits are immunoassay tools for the measurement of the protein glial cell derived neurotrophic factor, which is encoded by the GDNF gene in humans. Functionally, this protein is reported to be a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. The canonical protein structure is reported to have an amino acid length of 211 residues, a mass of 23.7 kDa, and is a member of the TGF-beta protein family. It is known to be secreted. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The GDNF gene has been associated with the disease, Hirschsprung disease. Other alias names for this target include ATF1, ATF2, HFB1-GDNF, HSCR3, glial cell line-derived neurotrophic factor, and ATF.
Some GDNF ELISA kits can detect targets at levels as low as 0.5 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.