The following defensin alpha 6 ELISA kits are useful research tools for the measurement of defensin alpha 6 in biological samples. In humans this protein is encoded by the DEFA6 gene. This protein is reported to be a host-defense peptide that contributes to intestinal innate immunity and mediates homeostasis at mucosal surfaces by forming higher-order oligomers that capture bacteria and prevent microbial invasion of the epithelium. The canonical protein structure is reported to have an amino acid length of 100 residues, a mass of 11 kDa, and is a member of the Alpha-defensin protein family. Its subcellular location is known to be in the cytoplasmic vesicles and is secreted. In addition, it is reported to be expressed in Paneth cells of the small intestine. In certain instances, it is also post-translationally cleaved. This protein may also be known as HD-6, defensin-6, defensin, alpha 6, Paneth cell-specific, and DEF6.
The detection range for different defensin alpha 6 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 150 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.