The following DNA topoisomerase II beta ELISA kits are useful research tools for the measurement of DNA topoisomerase II beta in biological samples. In humans this protein is encoded by the TOP2B gene. This protein has been described to function in neuronal development and B cell differentiation. The canonical protein structure is reported to have an amino acid length of 1626 residues, a mass of 183.3 kDa, and is a member of the Type II topoisomerase protein family. Its subcellular location is known to be in the nucleus. In addition, it is reported to be expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung.. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, B-cell immunodeficiency. This protein may also be known as TOPIIB, top2beta, DNA topoisomerase 2-beta, DNA topoisomerase II, 180 kD, DNA topoisomerase II, beta isozyme, and BILU.
The detection range for different DNA topoisomerase II beta ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.