Ready-to-use ELISA kits are available for the detection of TRM5 tRNA methyltransferase 5, an alias of the protein, tRNA methyltransferase 5. The official gene symbol is TRMT5. The protein, with a mass of 58.2 kDa and length of 509 residues, is reported to be cytoplasmic, nuclear and mitochondrial. It is a member of the Class I-like SAM-binding methyltransferase superfamily, TRM5/TYW2 family and may be known by other names, including: COXPD26, tRNA-N1G37 methyltransferase, tRNA (guanine-N(1)-)-methyltransferase, TRM5 tRNA methyltransferase 5 homolog, M1G-methyltransferase, and tRNA (guanine(37)-N1)-methyltransferase, and TRM5.