Anti-TICAM1 antibodies are used in the immunodetection of the protein TIR domain containing adaptor molecule 1. In humans, the canonical protein has a reported length of 712 amino acid residues and a mass of 76.4 kDa. Its subcellular localization is in the cytoplasmic vesicles, mitochondria, and cytoplasm. It is widely expressed across many tissue types. TICAM1 is known to be involved in innate immunity against invading pathogens. Post-translational modifications have been described, including ubiquitination, protein cleavage and phosphorylation. The TICAM1 gene has been associated with the disease, Encephalopathy. Synonyms for this target antigen include TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter protein inducing IFN-beta, proline-rich, vinculin and TIR domain-containing protein B, and TIR domain-containing adapter molecule 1. TICAM1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 110 citations in the literature describe the use of TICAM1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.