Anti-Calreticulin 3 antibodies are used in the immunodetection of the protein encoded by the CALR3 gene. In humans, the canonical protein has a reported length of 384 amino acid residues and a mass of 45 kDa. Its subcellular localization is in the ER. It is reported to have testis-specific expression. A member of the Calreticulin protein family, it is known to be involved with cell differentiation and protein folding. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include calsperin, cancer/testis antigen 93, testis secretory sperm-binding protein Li 226n, and calreticulin-2.