Anti-SNRPB antibodies are used in the immunodetection of the protein small nuclear ribonucleoprotein polypeptides B and B1. In humans, the canonical protein has a reported length of 240 amino acid residues and a mass of 24.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the SnRNP SmB/SmN protein family, SNRPB is reported to play a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Synonyms for this target antigen include COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', and CCMS. SNRPB gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 70 citations in the literature describe the use of SNRPB antibodies in research. These antibodies are most commonly used in Western Blot experiments, among other applications.