Anti-PDYN antibodies are used in the immunodetection of the protein prodynorphin. In humans, the canonical protein has a reported length of 254 amino acid residues and a mass of 28.4 kDa. It has been described to be a secreted protein. It is notably expressed in the caudate and cerebral cortex. A member of the Opioid neuropeptide precursor protein family, PDYN is known to be involved with chemical synaptic transmission. The PDYN marker can be used to identify Dorsal Excitatory Neurons.* Synonyms for this target antigen include PENKB, SCA23, proenkephalin-B, beta-neoendorphin-dynorphin, leu-enkephalin, and ADCA. PDYN gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Pdyn antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.
*HuBMAP Human Reference Atlas v1.4