Anti-PPM1L antibodies are used in the immunodetection of the protein protein phosphatase, Mg2+/Mn2+ dependent 1L. In humans, the canonical protein has a reported length of 360 amino acid residues and a mass of 41.1 kDa. Its subcellular localization is in the membrane. Up to 4 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the PP2C protein family, PPM1L is known to act as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. Synonyms for this target antigen include protein phosphatase 1L and PP2C epsilon. PPM1L gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PPM1L antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.