Anti-HSD17B4 antibodies are used in the immunodetection of the protein hydroxysteroid 17-beta dehydrogenase 4. In humans, the canonical protein has a reported length of 736 amino acid residues and a mass of 79.7 kDa. Its subcellular localization is in the peroxisomes. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Short-chain dehydrogenases/reductases (SDR) protein family, HSD17B4 is known to be involved with osteoblast differentiation. Synonyms for this target antigen include MFE-2, MFP-2, MPF-2, PRLTS1, SDR8C1, peroxisomal multifunctional enzyme type 2, 17-beta-HSD 4, and DBP. HSD17B4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HSD17B4 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.