Anti-ACTR3 antibodies are used in the immunodetection of the protein actin related protein 3. In humans, the canonical protein has a reported length of 418 amino acid residues and a mass of 47.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably widely expressed in many tissue types. A member of the Actin protein family, ACTR3 is reported to be an atp-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). Synonyms for this target antigen include ARP3 actin related protein 3 homolog, actin-like protein 3, and ARP3. ACTR3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 150 citations in the literature describe the use of ACTR3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.