Anti-VRK2 antibodies are used in the immunodetection of the protein VRK serine/threonine kinase 2. In humans, the canonical protein has a reported length of 508 amino acid residues and a mass of 58.1 kDa. Its subcellular localization is in the nucleus, mitochondria, ER, and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the CK1 Ser/Thr protein kinase protein family, VRK2 is reported to be a serine/threonine kinase that regulates several signal transduction pathways. Synonyms for this target antigen include vaccinia related kinase 2, vaccinia virus B1R-related kinase 2, and serine/threonine-protein kinase VRK2. VRK2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some VRK2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.