Anti-BIRC2 antibodies are used in the immunodetection of the protein baculoviral IAP repeat containing 2. In humans, the canonical protein has a reported length of 618 amino acid residues and a mass of 69.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the IAP protein family, BIRC2 is reported to be a multi-functional protein, which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Synonyms for this target antigen include HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1, baculoviral IAP repeat-containing protein 2, and API1. BIRC2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Over 270 citations in the literature describe the use of BIRC2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.