Anti-VDAC-1 antibodies enable researchers to detect and measure the VDAC-1 antigen in biological samples. This target is a reported synonym of the VDAC1 gene, which encodes voltage dependent anion channel 1. This protein is known to function in the apoptotic pathway and epithelial cell differentiation, among other biological roles. The human version of VDAC-1 has a canonical amino acid length of 283 residues and a protein mass of 30.8 kilodaltons. It is reported to be localized in the mitochondria and cell membrane of cells and widely expressed in many tissue types. VDAC-1 is a member of the Eukaryotic mitochondrial porin protein family.